Monday, July 14, 2008

How Prozac sent the science of depression in the wrong direction - The Boston Globe

A little late in posting this. From last Sunday's Boston Globe: How Prozac sent the science of depression in the wrong direction.

In sum, Prozac and its SSRI cousins purportedly treated depression by increasing the level of serotonin in the patient. Well, it turns out that it's not quite so. Raising or lowering serotonin, by itself, seems to have little direct effect on depression.

"The scientists showed that fluoxetine gave brain cells the ability to take on new roles and form new connections, which erased the symptoms of the disorder."
So, Prozac can help, but not in the way that we thought it did.

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